Further data are needed to advance beyond this. other embolism Hypertensive disorders of pregnancy Amniotic fluid embolism. Early consideration of the diagnosis after prompt resuscitation is needed. Pregnancy-Related Deaths by Urban-Rural Classifications Frequently Asked. Our featured article today is from the latest October 2022 APSF Newsletter by David Arnolds called, Recognition and Management of Amniotic Fluid Embolism: A Critical Role for Anesthesia Professionals on Labor and Delivery. With a rare condition additions to the literature are sparse. Case reports suggest that plasma exchange techniques may be helpful after initial resuscitation. Early diagnosis may be the best way to improve outcomes. The early data from the UK Register of cases show only 16% mortality, although there is significant maternal and neonatal morbidity. The case fatality rate and perinatal mortality associated with AFE are 1330 and 944, respectively. The estimated incidence of AFE is 1:15,200 and 1:53,800 deliveries in North America and Europe, respectively. Case-specific mortality may not be as high as previously thought. We conducted an evidence-based review of information bout amniotic fluid embolism (AFE). In Singapore, a study of postmortems found that over 30% of direct maternal deaths were caused by amniotic fluid embolism, the most common cause. In France, 13% of deaths are caused by amniotic fluid embolism, the third highest cause. Amniotic fluid embolism is considered an unpredictable and unpreventable event with an unknown cause. There has been a decrease in mortality from amniotic fluid embolism in the UK from 5.1 to 3.7 per million maternities, but it is still the fifth greatest cause of direct maternal death. With this rare condition we need to look for clues as to how to facilitate diagnosis and improve outcomes.Īmniotic fluid embolism continues to be a leading cause of maternal death. Morbidity and mortality from amniotic fluid embolism in the international context will be described, given the recent Confidential Enquiries into Maternal Deaths in the United Kingdom and other studies. In a new international study published in PLOS Medicine, Kathryn Fitzpatrick and colleagues 1 provide valuable clinical information about this rare complication, which. To review the recent literature on amniotic fluid embolism and how it may influence the clinical management and further study of the condition. Owing to its uncertain etiology, varying symptoms, rapid onset, and high fatality rate, amniotic fluid embolism (AFE) is one of the most challenging obstetric emergencies.
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